Download COBRA Txt
cobra-cli is a command line program to generate cobra applications and command files.It will bootstrap your application scaffolding to rapidlydevelop a Cobra-based application. It is the easiest way to incorporate Cobra into your application.
Download COBRA txt
Package cobra is a commander providing a simple interface to create powerful modern CLI interfaces.In addition to providing an interface, Cobra simultaneously provides a controller to organize your application code.
Documentation on the SBML standard is available on the SBML website and a description of a COBRA-compliant SBML file is provided in the Supplementary Material. Sample models in COBRA-compliant SBML may be downloaded from the BiGG knowledgebase (31) or draft models may be downloaded from the Model SEED (55). The model files must include the following information for all calculations: stoichiometry of each reaction, upper and lower bounds of each reaction and objective function coefficients for each reaction. Several functions within the Toolbox (47, 48) require information that is not, yet, in the SBML standard or scheduled for removal in SBML 3 and beyond. The gene-reaction associations are essential for relating the metabolic reactions to the genome and the subsystem is useful for ontological classification. Metabolite formulas and charges are necessary to make sure the model is physically consistent (no generation of mass or energy). See Supplementary Material.
where: KEGGFilename is the name of the reaction .lst file downloaded from KEGG (67, 68); compartment is a string denoting which compartment to generate exchange reactions for; iterations controls the number iterations to run the function; dictionary is an n by 2 cell array that maps metabolites to KEGG IDs; logFile is the name of the .mat file to save the solution to; and threshold is the minimum value that the biomass function can take for the model to be considered growing.
The Java Remote Method Invocation (RMI) mechanism and the Common Object Request Broker Architecture (CORBA) are the two most important and widely used distributed object systems. Each system has its own features and shortcomings. Both are being used in the industry for various applications ranging from e-commerce to health care. Selecting which of these two distribution mechanisms to use for a project is a tough task. This article presents an overview of RMI and CORBA, and more importantly it shows how to develop a useful application for downloading files from remote hosts. It then:
This application allows a client to transfer (or download) any type of file (plain text or binary) from a remote machine. The first step is to define a remote interface that specifies the signatures of the methods to be provided by the server and invoked by clients.
The remote interface for the file download application is shown in Code Sample 1. The interface FileInterface provides one method downloadFile that takes a String argument (the name of the file) and returns the data of the file as an array of bytes.
The next step is to develop a client. The client remotely invokes any methods specified in the remote interface ( FileInterface). To do so however, the client must first obtain a reference to the remote object from the RMI registry. Once a reference is obtained, the downloadFile method is invoked. A client implementation is shown in Code Sample 4. In this implementation, the client accepts two arguments at the command line: the first one is the name of the file to be downloaded and the second one is the address of the machine from which the file is to be downloaded, which is the machine that is running the file server.
where fileName is the file to be downloaded and machineName is the machine where the file is located (the same machine runs the file server). If everything goes ok then the client exists and the file downloaded is on the local machine.
To run the client we mentioned that you need a copy of the interface and stub. A more appropriate way to do this is to use RMI dynamic class loading. The idea is you do not need copies of the interface and the stub. Instead, they can be located in a shared directory for the server and the client, and whenever a stub or a skeleton is needed, it is downloaded automatically by the RMI class loader. To do this you run the client, for example, using the following command: java -Djava.rmi.server.codebase= FileClient fileName machineName.
When defining a CORBA interface, think about the type of operations that the server will support. In the file transfer application, the client will invoke a method to download a file. Code Sample 5 shows the interface for FileInterface. Data is a new type introduced using the typedef keyword. A sequence in IDL is similar to an array except that a sequence does not have a fixed size. An octet is an 8-bit quantity that is equivalent to the Java type byte.
Note that the downloadFile method takes one parameter of type string that is declared in. IDL defines three parameter-passing modes: in (for input from client to server), out (for output from server to client), and inout (used for both input and output).
Now, we provide an implementation to the downloadFile method. This implementation is known as a servant, and as you can see from Code Sample 6, the class FileServant extends the _FileInterfaceImplBase class to specify that this servant is a CORBA object.
The next step is to develop a client. An implementation is shown in Code Sample 8. Once a reference to the naming service has been obtained, it can be used to access the naming service and find other services (for example the FileTransfer service). When the FileTransfer service is found, the downloadFile method is invoked.
In the file transfer application, the client (in both cases RMI and CORBA) needs to know the name of the file to be downloaded in advance. No methods are provided to list the files available on the server. As an exercise, you may want to enhance the application by adding another method that lists the files available on the server. Also, instead of using a command-line client you may want to develop a GUI-based client. When the client starts up, it invokes a method on the server to get a list of files then pops up a menu displaying the files available where the user would be able to select one or more files to be downloaded.
To facilitate this, we provide a script that can download multiple PDB archive files by providing a file containing a comma-separated list of PDB ids. It requires that the curl tool is installed in your computer.
Such a list of PDB ids can be obtained by selecting "PDB IDs" in the "Tabular Report" drop-down available in any search results page. The "Download IDs" button will download a file containing a comma-separated list of PDB ids. Lists of PDB ids matching certain criteria can also be obtained programmatically with our Search API.
In some cases it is not possible to provide a list of completions in advance. Instead, the list of completions must be determined at execution-time. In a similar fashion as for static completions, you can use the ValidArgsFunction field to provide a Go function that Cobra will execute when it needs the list of completion choices for the nouns of a command. Note that either ValidArgs or ValidArgsFunction can be used for a single cobra command, but not both.Simplified code from helm status looks like:
You may have noticed the use of cobra.ShellCompDirective. These directives are bit fields allowing to control some shell completion behaviors for your particular completion. You can combine them with the bit-or operator such as cobra.ShellCompDirectiveNoSpace cobra.ShellCompDirectiveNoFileComp
Important: You should not leave traces that print directly to stdout in your completion code as they will be interpreted as completion choices by the completion script. Instead, use the cobra-provided debugging traces functions mentioned above.
Important: You should not leave traces that print to stdout in your completion code as they will be interpreted as completion choices by the completion script. Instead, use the cobra-provided debugging traces functions mentioned further above.
Cobra supports native Zsh completion generated from the root cobra.Command.The generated completion script should be put somewhere in your $fpath and be named_. You will need to start a new shell for the completions to become available.
Cobra supports native Fish completions generated from the root cobra.Command. You can use the command.GenFishCompletion() or command.GenFishCompletionFile() functions. You must provide these functions with a parameter indicating if the completions should be annotated with a description; Cobra will provide the description automatically based on usage information. You can choose to make this option configurable by your users.
Cobra can generate PowerShell completion scripts. Users need PowerShell version 5.0 or above, which comes with Windows 10 and can be downloaded separately for Windows 7 or 8.1. They can then write the completions to a file and source this file from their PowerShell profile, which is referenced by the $Profile environment variable. See Get-Help about_Profiles for more info about PowerShell profiles.
Coming back to your question: the Affymetrix dataset you linked to is indeed a custom-made Affymetrix array. To reanalyse this, you will need the raw data (CEL) and chip definition (CDF) files. You can download the CEL files from GEO, but the CDF GEO provides for this array is a weird one: it is in TXT format, and although there are TXT-ASCII based CDFs, the format and content of the available CDF doesn't adhere to the expected standards. In other words, you cannot convert it into a CDF-environment (which is needed for BioC/R to normalize the data) using the library makecdfenv() [that is what James was referring to in his 1st post...]. I would suggest you get in touch with the submitter of that dataset and ask them directly for that CDF file. Alternatively you could maybe use the normalized data that also can be downloaded from GEO.Please also have a look at the limma user's guide, which provides an entry on how to normalize one- or two-colour Agilent data. For Affymetrix datasets, this, this and this site are also useful to get started. 041b061a72